HOTLAB 2023 is the 59th edition of the annual meeting on Hot Laboratories and remote handling. This year’s meeting was hosted by Oak Ridge National Laboratory. The first meeting was held in Cadarache, France, in 1963. Since then, the purpose of the annual meeting is to share experience, know-how and to start the collaboration in all aspect of nuclear research and development (R&D). This meeting is intended for technicians, operators, engineers, researchers, suppliers, and managers working at and for nuclear R&D facilities – hot cells.